Li Dong   Ph. D
	Lectures   Master Supervisor
	Email：Dongli@sxu.edu.cn

EDUCATION AND WORK BACKGROUNDS

SCIENTIFIC RESEARCH SPECIFICITY

The optimal strategies for cancer prevention and control are being investigated, focusing on the early detection and early treatment of cervical cancer and upper digestive tract cancer by identifying molecular biomarkers related with specific structures of pathogens and the cell signal pathway, and verifying their predicting value by means of population-based epidemiology. The specific researches were listed as follows:

1. Role of methylation of HPV DNA and host cell in predicting the risk of cervical cancer；
2. Immunogenic mechanism of HPV persistent infection and clearance；
3. HPV oncogenes on the regulating of cervical cancer stem cell;
4. The association of microbiome of upper digestive tract with the esophagus cancer.

REPRESENTATIVE OUTCOMES

Scientific programs:  Taking charge of Shanxi province Science Fund for Youths (2012-2015) and taking parting in the National Natural Science Foundation China-National Institute Health USA (2017-2020), and also CMB Open Competition Research Program Health Policy and System Sciences (2017-2020).

Patents：  China invention patent, one item

                  Patent for utility models, one item

Books： Three medical books as the co-author.

NEWEST ARTICLES IN FIVE YEARS

1. Dong L, Hu S, Zhang Q, et al. Risk prediction of cervical cancer and precancers by type-specific human papillomavirus: evidence from a population-based cohort study in China. Cancer Prevention Research. Cancer Prev Res, 2017,5:1–7. IF=3.985.
2. Dong L, Feng RM, Zhang L, et al. Prospective comparison of hybrid capture 2 and SPF10-LiPA for carcinogenic human papillomavirus detection and risk prediction of cervical cancer: a population-based cohort study in China. Journal of gynecologic oncology. 2017, 28(5):e66. IF= 3.140.
3. Dong L, Lin CQ, Li L, et al. An evaluation of clinical performance of FTA cards for HPV 16/18 detection using cobas 4800 HPV Test compared to dry swab and liquid medium[J]. Journal of Clinical Virology, 2017, 94:67. IF= 3.051.
4. Dong L, Wang M, Zhao XL, et al. Human papillomavirus viral load as a useful tool for non-16/18 high-risk human papillomavirus positive women: a prospective screening cohort study. Gynecologic Oncology. 2017, in press. IF=4.959
5. Dong L, Li TY, Li L, et al. Multiple Human papillomavirus infections in cervical adenocarcinoma in a multi-center biopsy-based clinical study. Journal of clinical microbiology, 2017, in press, IF=3.712
6. Zhang Q, Dong L, Hu S, et al. Risk Stratification and Long-term Risk Prediction of E6 Oncoprotein in a Prospective Screening Cohort in China. International Journal of Cancer, 2017. 141(6):1110-1119. IF=6.513.
7. Zhao XL, Hu SY, Zhang Q, Dong L, Feng RM, Han R, Zhao FH. High-risk human papillomavirus genotype distribution and attribution to cervical cancer and precancerous lesions in a rural Chinese population. J Gynecol Oncol. 2017 Jan;28:e30. IF=3.140.
8. Zhao J, Zhao J, Du F, Zhang Y, Shen G,Zhu H, Ji F, Ma F, Dong L,et al. Cardia and non-cardia gastric cancer have similar stage-for-stage prognoses after R0 resection: a large-scale, multicenter study in China[J]. Journal of Gastrointestinal Surgery, 2016, 20(4): 700-707. IF=2.807.
9. Dong L, Hu Shangying, Zhang Qian, Changes in genotype prevalence of human papillomavirus over 10-year follow-up of a cervical cancer screening cohort. Chinese Journal of Epidemiology. 2017,38(1):20-25.(in Chinese)
10. Dong L, Qiao YL. HPV and cervical adenocarcinoma. Journal of practical obstetrics and gynecology. 2016,32(8):1-2. (in Chinese)