Shuhua Shan   Ph.D
	Associate Professor   Master Supervisor
	Email: ssh@sxu.edu.cn

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 Educational background:

September 2011-december 2014: Doctor's degree, Biochemistry and Molecular Biology, Shanxi University;

September 2002-June 2005: Master's degree, botany, Huazhong Agricultural University;           

September 1998 –July 2002: Bachelor's degree, Biology Education, Shanxi Normal University.   

 

Working Experience：

July 2017-Present: Associate professor of Shanxi University;        

December 2015 - June 2017: Associate professor of Taiyuan Normal University;      

October 2005 – November 2015: Lecturer of Taiyuan Normal University.

 

Major Research Interests:

1. Screening and preparation of anti-tumor functional molecules in special plant resources and their safety evaluation.

2. Anti-tumor effects of special plant-derived active molecules and related molecular targets and mechanisms.

Scientific research projects：

2016-2018: National Natural Science Foundation of China for Youths (General Program, 200 thousand), Item Number: 31500630

2015-2017：Shanxi Province Science Foundation for Youths (General Program, 30 thousand), Item Number: 2015021200.

2015-2017：Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi (General Program, 20 thousand), Item Number: 2015175.

 

Representative papers:

1. Shuhua Shan, Jiangying Shi, Peng Yang, Bin Jia, Haili Wu, XiaoLi Zhang, Zhuoyu Li*. Apigenin restrains colon cancer cell proliferation via targetedly blocking the PKM2-dependent glycolysis. Journal of Agricultural and Food Chemistry. 2017, 65(37):8136-8144.

2. Shuhua Shan, Jiangying Shi，Zhen Li，Zhuoyu Li et al. Targeted anti-colon cancer activities of a millet bran-derived peroxidase were mediated by elevated ROS generation. Food & Function, 2015(6), 2331-2338.

3. Shuhua Shan, Zongwei Li, Songjia Guo, Zhuoyu Li*, Tonglin Shi, Jiangying Shi. A millet bran-derived peroxidase inhibits cell migration by antagonizing STAT3-mediated epithelial-mesenchymal transition in human colon cancer. Journal of functional foods, 2014 (10): 444–455.

4. Shuhua Shan, Zongwei Li, Ian P. Newton , Chao Zhao, Zhuoyu Li*, Maolin Guo. A novel protein extracted from foxtail millet bran displays anti-carcinogenic effects in human colon cancer cells. Toxicology letters, 2014, 227: 129-138.

5. Jiangying Shi^#, Shuhua Shan^#, Zongwei Li, Hanqi Li, Xinfeng Li, Zhuoyu Li*. Bound polyphenol from foxtail millet bran induces apoptosis in HCT-116 cell through ROS generation. Journal of functional foods, 2015,17,958-968.