Zhiqiang Yang Ph.D
	Lecturer & Master Supervisor
	Email: yzq2021@sxu.edu.cn

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Research interests

1.  Regulation of the cGAS-STING signaling pathway by Mycobacterium tuberculosis effector proteins.

2.  Bacterial metabolic reprogramming under antibiotic stress(drug-resistant Mycobacterium tuberculosis and drug-resistant Gram-negative bacteria).

3.  Risk assessment and early warning of foodborne pathogens.

Professional experience

2021. 04-Present   Institute of Biomedical Sciences, Shanxi University, lecturer

2015. 07-2016.08  Food Safety and Technology Research Centre, The Hong Kong Polytechnic University, Research Assistant

Educational Background

2016. 09-2020. 08 Ph.D., National Key Laboratory of Veterinary Public Health and Safety, China Agricultural University

2013. 08-2015. 06 M.S., Key Laboratory for Zoonoses Research, Ministry of Education, Jilin University

2009. 09-2013. 06 B.S., Key Lab of Ecological Animal Husbandry and Environmental Veterinary Medicine of Shanxi Province, Shanxi Agricultural University

Present students

Genetics, Microbiology

Ms. Zhangqi Yan, Ms. Yiping Ren, Ms. Meiqi Gao, Ms. Qin Zeng, Mr. Mingke Song, Mr. Yifan Liang

Food Processing and Safety, Food and nutrition

Ms. Shasha Luo, Ms. Pengni Chai

Selected Publication

1. Yang Z, Huang Y, Zhou H, Zhang R, Zhu K*. Persistent Carbapenem-resistant Klebsiella pneumoniae: a Trojan Horse[J]. The Lancet Infectious Diseases, 2018, 18(1): 22-23.

2. Yang Z, Song M, Li X, Zhang Q, Shen J, Zhu K*. Synergy of outer membrane disruptor SLAP-S25 with hydrophobic antibiotics against Gram-negative pathogens[J]. Journal of Antimicrobial Chemotherapy, 2023, 78(1): 263-271.

3. Yang Z, Sun Q, Chen S, Ding S, Zhang R*, Zhu K*. Genomic and Phenotypic Analysis of Persistent Carbapenem-Resistant Klebsiella pneumoniae Isolates from a 5-Year Hospitalized Patient[J]. Microbial Drug Resistance, 2020, 27(8): 1117-1125.

4. Ding L#, Yang Z#, Lu J, Ma L, Liu Y, Wu X, Yao W*, Zhang X*, Zhu K. Characterization of Phenotypic and Genotypic Traits of Klebsiella pneumoniae from Lung Cancer Patients with Respiratory Infection[J]. Infection & Drug Resistance, 2020, 13: 237-245.

5. Ma F#, Zhou H#, Yang Z#,Wang C, An Y, Ni L, Liu M, Wang Y, Yu L*. Gene Expression Profile Analysis and Target Gene Discovery of Mycobacterium tuberculosis Biofilm[J]. Applied Microbiology & Biotechnology, 2021, 105(12): 5123-5134.

6. Meng C, Chen G, Liu Y, Wen D, Cui J, Dong L, Yang Z, Meng H, Gao Y, Feng J, Cui X, Wu C. miR-4687-5p Affects Intracellular Survival of Mycobacterium tuberculosis through Its Regulation of NRAMP1 Expression in A549 Cells. Microorganisms. 2024 Jan 22;12(1):227. doi: 10.3390/microorganisms12010227.

7. Ai W, Yang Z, Ma Y, Han X, Chen Y, Zhu K*, Wang Z*. Combined Tetraphenylethylene Fluorogens with Positive Charge for Imaging Capsule-covered Pathogens[J]. Analyst, 2020, 145(20): 6435-6440.

8. Wu S, Yang Z, Liu F, Peng W, Qu S, Li Q, Song X, Zhu K*, Shen J*. Antibacterial Effect and Mode of Action of Flavonoids from Licorice Against Methicillin-Resistant Staphylococcus aureus[J]. Frontiers in Microbiology, 2019, 10.

9. Guo J, Liu D, Yang Z, Weng W, Chan EWC, Zeng Z, Wong KY, Lin P*, Chen S*. A Photoelectrochemical Biosensor for Rapid and Ultrasensitive Norovirus Detection[J]. Bioelectrochemistry, 2020, 136: 107591.

10. Hu M, Guo J, Cheng Q, Yang Z, Chan EWC, Chen S*, Hao Q*. Crystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance[J]. Scientific Reports, 2016, 6: 38793.