Jiao Feng Ph.D
	Associate Professor & Master Supervisor
	Email: fengjiao2018@sxu.edu.cn

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Research Interests

1. Molecular      mechanisms of drug resistance in bacteria and research on phage therapy.

2. Molecular      mechanisms of non-coding region SNPs in Regulating Gene Expression and      Influencing Susceptibility to Human Tuberculosis.

Recruitment Areas

1. Academic      Master’s Programs: Genetics, Microbiology, Biochemistry      and Molecular Biology

2. Professional      Master’s Program: Biological Technology and      Engineering

Research Projects

1. Central Guidance on Local Science and Technology Development Fund of Shanxi Province (YDZJSX20231A003): Molecular mechanisms of non-coding region SNPs regulating gene expression and influencing human tuberculosis susceptibility. 2023/07–2026/06, ¥400,000 (PI).

2. Shanxi University "Wenying Young Scholar" Talent Program: 2024–2026, ¥450,000 (PI).

3. Industry Collaboration Project: Isolation, identification, and bactericidal efficacy evaluation of Pseudomonas aeruginosa phages (PI).

4. National Natural Science Foundation of China (82002207): Novel Mobile Elements Related to Multidrug Resistance in Clinical Isolates of Raoultella ornithinolytica. 2021/01–2023/12, ¥240,000 (PI).

5. Natural Science Foundation of Shanxi Province (201901D211136): Characteristics, genomics, and therapeutic potential  of Klebsiella pneumoniae phages against multidrug-resistant infections. 2019/09–2022/09 (PI).

6. Shanxi Higher Education Innovation Project (2019L0040):      Mechanisms of IncHI5 plasmid-mediated acquisition and evolution of  antibiotic resistance genes in clinical Raoultella. 2019/07–2021/07 (PI).

Master students

Representative Publications

1. Jiao Feng, Changxin Wu, Dongsheng Zhou, Lingfei Hu, Kai Mu*, Zhe Yin*. Insights into incompatible plasmids in multidrug-resistant Raoultella superbugs. BMC Microbiology. 2025, 25(1):55.

2. Jiao Feng, Zhiwei Song, Piaoiao Dai, Huimin Chen, Dakang Hu, Lian Yu, Jin Zhang, Xinhua Luo*. Genomic analysis of IMP-8-producing Enterobacter hormaechei with a novel plasmid pK432-IMP. Journal of Global Antimicrobial Resistance. 2024, 39:250-256.

3. Feng J, Li F, Sun L, Dong L, Gao L, Wang H, Yan L, Wu C. Characterization and genome analysis of phage vB_KpnS_SXFY507 against Klebsiella pneumoniae and efficacy assessment in Galleria mellonella larvae. Front Microbiol. 2023, 30;14:1081715.

4. Luo X, Yin Z, Yu L, Zhang J, Hu D, Xu M, Wang P, Wang F and Feng J^*. Genomic analysis of chromosomal cointegrated blaNDM-1-carrying ICE and bla_RSA-1-carrying IME from clinical multidrug resistant Aeromonas caviae. Front Cell Infect Microbiol. 2023, 13:1131059. (corresponding author)

5. Yang M, Liu D, Li X, Xiao C, Mao Y, He J, Feng J^*, Wang L^*. Characterizations of bla_CTX−M−14 and bla_CTX−M−64 in a clinical isolate of Escherichia coli from China. Front Microbiol. 2023 14:1158659. (corresponding author)

6. Li F, Li L, Zhang Y, Bai S, Sun L, Guan J, Zhang W, Cui X, Feng J^*, Tong Y^*. Isolation and characterization of the novel bacteriophage vB_SmaS_BUCT626 against Stenotrophomonas maltophilia. Virus Genes. 2022, 58(5):458-466. (corresponding author)

7. Jiao Feng^*, Liting Gao, Lu Li; Zhijun Zhang, Changxin Wu, Fei Li^*, Yigang Tong^*, Characterization and genome analysis of novel Klebsiella phage BUCT556A with lytic activity against carbapenemase-producing Klebsiella pneumoniae, Virus Research, 2021, 303: 0-198506.

8. Jiao Feng, Zhe Yin, Qiangyuan Zhao, Yachao Zhao, Defu Zhang, Xiaoyuan Jiang, Weili Wu, Weijun Chen, Hui Wang, Yajun Song, Yigang Tong, Jinglin Wang^*, Yanjun Li^*, and Dongsheng Zhou^*, Genomic Characterization of Novel IncFII-Type Multidrug Resistant Plasmids p0716-KPC and p12181-KPC from Klebsiella Pneumoniae, Scientific Reports, 2017, 7.

9. Jiao Feng, Yefeng Qiu, Zhe Yin, Weijun Chen, Huiying Yang, Wenhui Yang, Jie Wang, Yingjie Gao, Dongsheng Zhou^*, Coexistence of a novel KPC-2-encoding MDR plasmid and an NDM-1-encoding pNDM-HN380-like plasmid in a clinical isolate of Citrobacter freundii. Journal of Antimicrobial Chemotherapy, 2015, 70(11):2987.

10. Luo X, Yu L, Feng J, Zhang J, Zheng C, Hu D, Dai P, Xu M, Li P, Lin R, Mu K. Emergence of Extensively Drug-Resistant ST170 Citrobacter portucalensis with Plasmids pK218-KPC, pK218-NDM, and pK218-SHV from a Tertiary Hospital, China. Microbiol Spectr. 2022, 26;10(5):e0251022. (co-first author)

11. Qifeng Sun^#, Jiao Feng^#, Yigang Tong, Luhua Liang, Fei Zhai, Rongwu Xiang, Genomic characterization of IncpA1763-KPC: IncFIIK7 type plasmids p13294-KPC and pA1966-NR from Klebsiella pneumoniae. Future Microbiology, 2020, 15(9):713-721. (co-first author)

12. Bing Li^#, Jiao Feng^#, Zhe Zhan, Zhe Yin, Qiyu Jiang, Ping Wei, Xingming Chen, Bo Gao, Jun Hou, Panyong Mao, Weili Wu, Weijun Chen, Yigang Tong, Jinglin Wang, Boan Li^*, Dongsheng Zhou^*, Dissemination of KPC-2-Encoding IncX6 Plasmids among Multiple Enterobacteriaceae Species in a Single Chinese Hospital, Frontiers in Microbiology, 2018, 9. (co-first author)

13. Haihong Fang^#, Jiao Feng^#, Yuanhong Xu, Ying Zhang, Zhe Zhan, Zhe Yin, Xiongbo Duan, Bo Gao, Yigang Tong, Jinglin Wang, Yanping Luo^*, Erhei Dai^*, and Dongsheng Zhou^*, Sequencing of pT5282-CTXM, p13190-KPC and p30860-NR, and Comparative Genomics Analysis of IncX8 Plasmids, International Journal of Antimicrobial Agents, 2018, 52: 210-217. (co-first author)

14. Lining Shi#, Feng Jiao#, Zhe Zhan, Yuzong Zhao, Haijian Zhou, Haifeng Mao, Yingjie Gao, Ying Zhang, Zhe Yin, Bo Gao, Yigang Tong, Yanping Luo, Defu Zhang*, Dongsheng Zhou*. Comparative analysis of blaKPC-2- and rmtB-carrying IncFII-family pKPC-LK30/pHN7A8 hybrid plasmids from Klebsiella pneumoniae CG258 strains disseminated among multiple Chinese hospitals, Infection and Drug Resistance, 2018.10, Volume 11: 1783~1793. (co-first author)

Patents

1. Feng, J., Sun, L., Wu, C., Li, F., et al. A lytic phage targeting multidrug-resistant Klebsiella pneumoniae and its application. Chinese Invention Patent, ZL 2022 1 0588905.X (Authorized: November 14, 2023).

2. Yin, Z., Feng, J., Zhou, D., et al. A novel transposon Tn6505 and its application. Chinese Invention Patent, ZL 2019 1 0255401.4 (Authorized: December 18, 2020).

3. Yin, Z., Zhao, Y., Zhou, D., Sun, Y., Feng, J., et al. Plasmid p16005813A and its application. Chinese Invention Patent, ZL 2019 1 0247810.X (Authorized: February 26, 2021).