Yina An Ph.D
	Lecturer & Master’s Supervisor
	Email: anyina@sxu.edu.cn

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Research interests

She is mainly engaged in research related to disease and host immunity, and current research mainly focuses on:

1. Mycobacterium tuberculosis and Mycobacterium bovis infection, dissemination and host immune regulation.

2. Research on new intervention techniques for tuberculosis and zoonotic tuberculosis.

 

Research projects

Participates in the sub-topic "Impact and Mechanisms of Niche Stressors on the Persistence of Drug-Resistant Bacteria" under the National Key Research and Development Program of China (Project No. 2022YFD1800400).

 

Publications

1. An Y, Tan S, Zhang P, Yang J, Wang K, Zheng R, Qiao L, Wang Y*, Dong Y*. Inactivation of MST1/2 controls macrophage polarization to affect macrophage-related disease via YAP and non-YAP mechanisms. International Journal of Biological Sciences, 2024, 20: 1004-1023.

2. An Y, Tan S, Yang J, Gao, T*, Dong Y*. The potential role of Hippo pathway regulates cellular metabolism via signaling crosstalk in disease-induced macrophage polarization. Frontiers in Immunology, 2024, 14: 0.

3. An Y, Ren Y, Wang J, Zang J, Gao M, Wang H, Wang S*, Dong Y*. MST1/2 in PDGFRα⁺ cells negatively regulates TGF-β-induced myofibroblast accumulation in renal fibrosis. American Journal of Physiology-Renal Physiology, 2022, 322: F512–F526.

4. Bai Q#, Wang Z#, An Y#, Tian J, Li Z, Yang Y, Dong Y, Chen M*, Liu T*. Chitosan-functionalized graphene oxide as adjuvant in HEV P239 vaccine. Vaccine, 2022, 40: 7613-7621.

5. Fan K#, An Y#, Wang Z, Yin W, Sun N, Sun Y, Khan A, Li H*. Antibacterial activity of recombinant porcine β-defensin 2. Pakistan Veterinary Journal, 2019, 39(3): 411-415.

6. An Y, Tan S, Feng L, Bao M, Liu M, Yin Q, Dong Y*. Effects of Irisin on tissue damage and bacterial clearance in mice infected with Escherichia coli. Acta Veterinaria et Zootechnica Sinica, 2024, 55(11): 5267-5277.

7. An Y, Tan S, Liu T, Dong Y*. SGK promotes tumor growth in mice via inhibiting tumor suppressor gene p27 protein. Chinese Journal of Veterinary Medicine. 2023, 11(59): 1-10.

8. An Y, Yang J, Gao M, Dong Y*. Research progress on the function of African swine fever virus encoded protein and vaccine. Animals Breeding and Feed, 2021, 10: 107-114.

9. An Y, Yuan H, Fan K, Yin W, Sun N, Jiang J, Li H*. Recombinant porcine CD40L induced IL-1β and TNF-α secretion from porcine alveolar macrophages in vitro. Chinese Veterinary Science, 2020, 50(02): 233-239.

 

Patent

An Y, Dong Y, Wang S, Tan S. Inhibition of MST1/2 or MST1/2 knockout in macrophages for the treatment of infectious polymyxin-resistant bacterial diseases. 2023.07.17, China, 202310323680.X.