冯娇 博士 | |
副教授 硕士生导师 | |
Email:fengjiao2018@sxu.edu.cn |
教育和工作经历:
2018年6月毕业于军事科学院军事医学研究院微生物流行病研究所,获博士学位;2018年10月全职加入山西大学生物医学研究院。
主要研究方向:
1. 细菌耐药机制及防治策略
2. 结核病易感机制研究
科研项目:
1.中央引导地方科技发展资金项目,YDZJSX20231A003,非编码区SNP调控基因表达影响人类结核病易感性的分子机制研究,2023/07-2026/06,40万元,在研,主持。
2. 企业合作项目,铜绿假单胞菌噬菌体的分离鉴定及其杀菌能力评估,在研,主持。
3. 国家青年科学基金项目,82002207,介导临床解鸟氨酸拉乌尔菌多药耐药的新型移动元件研究,2021/01-2023/12,24万元,已结题,主持。
4. 山西省应用基础研究项目,201901D211136,肺炎克雷伯菌噬菌体的特性、基因组学及抗多药耐药菌感染的潜力研究,2019/09-2022/09,已结题,主持。
5. 山西省高等学校科技创新项目,2019L0040,IncHI5质粒介导临床拉乌尔菌耐药基因获得及进化的机制研究,2019/07-2021/07,已结题,主持。
6. 国家自然科学基金面上项目,82070691,结节硬化症糖原储积异常分子细胞生物学病理机制研究,2021/01-2024/12,58万元,在研,参加。
7. 国家青年科学基金项目,31801662,IncA/C质粒介导食源性副溶血弧菌ESBLs基因获得及进化的分子机制研究,2019/01-2021/12,22万元,已结题,参加。
8. 国家自然科学基金面上项目,31671290,副溶血弧菌毒力基因表达的密度感应调控机制,2017/01-2020/12,60万元,已结题,参加。
9. 国家重点研发专项,2016YFC1200100,重要新发突发病原体发生与传播机制研究,2016/07-2018/12,58.5万元,已结题,参加。
发表文章:
1. Feng J, Li F, Sun L, Dong L, Gao L, Wang H, Yan L, Wu C. Characterization and genome analysis of phage vB_KpnS_SXFY507 against Klebsiella pneumoniae and efficacy assessment in Galleria mellonella larvae. Front Microbiol. 2023, 30;14:1081715.
2. Luo X, Yin Z, Yu L, Zhang J, Hu D, Xu M, Wang P, Wang F and Feng J*. Genomic analysis of chromosomal cointegrated blaNDM-1-carrying ICE and blaRSA-1-carrying IME from clinical multidrug resistant Aeromonas caviae. Front Cell Infect Microbiol. 2023, 13:1131059.(通讯作者)
3. Yang M, Liu D, Li X, Xiao C, Mao Y, He J, Feng J*, Wang L*. Characterizations of blaCTX−M−14 and blaCTX−M−64 in a clinical isolate of Escherichia coli from China. Front Microbiol. 2023 14:1158659.(通讯作者)
4. Jiao Feng*, Liting Gao, Lu Li; Zhijun Zhang, Changxin Wu, Fei Li*, Yigang Tong*, Characterization and genome analysis of novel Klebsiella phage BUCT556A with lytic activity againstcarbapenemase-producing Klebsiella pneumoniae, Virus Research, 2021, 303: 0-198506.
5. Jiao Feng, Zhe Yin, Qiangyuan Zhao, Yachao Zhao, Defu Zhang, Xiaoyuan Jiang, Weili Wu, Weijun Chen, Hui Wang, Yajun Song, Yigang Tong, Jinglin Wang*, Yanjun Li*, and Dongsheng Zhou*, Genomic Characterization of Novel IncFII-Type Multidrug Resistant Plasmids p0716-KPC and p12181-KPC from Klebsiella Pneumoniae, Scientific Reports, 2017, 7.
6. Jiao Feng, Yefeng Qiu, Zhe Yin, Weijun Chen, Huiying Yang, Wenhui Yang, Jie Wang, Yingjie Gao, Dongsheng Zhou*, Coexistence of a novel KPC-2-encoding MDR plasmid and an NDM-1-encoding pNDM-HN380-like plasmid in a clinical isolate of Citrobacter freundii. Journal of Antimicrobial Chemotherapy, 2015, 70(11):2987.
7. Li F, Li L, Zhang Y, Bai S, Sun L, Guan J, Zhang W, Cui X, Feng J, Tong Y. Isolation and characterization of the novel bacteriophage vB_SmaS_BUCT626 against Stenotrophomonas maltophilia. Virus Genes. 2022, 58(5):458-466.(通讯作者)
8. Luo X, Yu L, Feng J, Zhang J, Zheng C, Hu D, Dai P, Xu M, Li P, Lin R, Mu K. Emergence of Extensively Drug-Resistant ST170 Citrobacter portucalensis with Plasmids pK218-KPC, pK218-NDM, and pK218-SHV from a Tertiary Hospital, China. Microbiol Spectr. 2022, 26;10(5):e0251022.(共同一作)
9. Qifeng Sun#, Jiao Feng#, Yigang Tong, Luhua Liang, Fei Zhai, Rongwu Xiang, Genomic characterization of IncpA1763-KPC: IncFIIK7 type plasmids p13294-KPC and pA1966-NR from Klebsiella pneumoniae. Future Microbiology, 2020, 15(9):713-721.(共同一作)
10. Bing Li#, Jiao Feng#, Zhe Zhan, Zhe Yin, Qiyu Jiang, Ping Wei, Xingming Chen, Bo Gao, Jun Hou, Panyong Mao, Weili Wu, Weijun Chen, Yigang Tong, Jinglin Wang, Boan Li*, Dongsheng Zhou*, Dissemination of KPC-2-Encoding IncX6 Plasmids among Multiple Enterobacteriaceae Species in a Single Chinese Hospital, Frontiers in Microbiology, 2018, 9.(共同一作)
11. Haihong Fang#, Jiao Feng#, Yuanhong Xu, Ying Zhang, Zhe Zhan, Zhe Yin, Xiongbo Duan, Bo Gao, Yigang Tong, Jinglin Wang, Yanping Luo*, Erhei Dai*, and Dongsheng Zhou*, Sequencing of pT5282-CTXM, p13190-KPC and p30860-NR, and Comparative Genomics Analysis of IncX8 Plasmids, International Journal of Antimicrobial Agents, 2018, 52: 210-217.(共同一作)
12. Lining Shi#, Feng Jiao#, Zhe Zhan, Yuzong Zhao, Haijian Zhou, Haifeng Mao, Yingjie Gao, Ying Zhang, Zhe Yin, Bo Gao, Yigang Tong, Yanping Luo, Defu Zhang*, Dongsheng Zhou*. Comparative analysis of blaKPC-2- and rmtB-carrying IncFII-family pKPC-LK30/pHN7A8 hybrid plasmids from Klebsiella pneumoniae CG258 strains disseminated among multiple Chinese hospitals, Infection and Drug Resistance, 2018.10, Volume 11: 1783~1793.(共同一作)
授权的专利:
1. 冯娇,孙梨,吴长新,李飞等,一株多药耐药肺炎克雷伯菌噬菌体及其应用,2023年11月14日授权,中国发明专利,专利号:ZL 2022 1 0588905.X
2. 殷喆,冯娇,周冬生等,一种新型转座子Tn6505及其应用,2020年12月18日授权,中国发明专利,专利号:ZL 2019 1 0255401.4
3. 殷喆,赵月娥,周冬生,孙岩松,冯娇等,一种质粒p16005813A及其应用,2021年02月26日授权,中国发明专利,专利号:ZL 2019 1 0247810. X
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