冯娇 博士
	副教授 硕士生导师
	Email：fengjiao2018@sxu.edu.cn

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教育和工作经历：

2018年6月毕业于军事科学院军事医学研究院微生物流行病研究所，获博士学位；2018年10月全职加入山西大学生物医学研究院。

主要研究方向：

1. 细菌耐药机制及防治策略

2. 结核病易感机制研究

科研项目：

1. 国家青年科学基金项目，82002207，介导临床解鸟氨酸拉乌尔菌多药耐药的新型移动元件研究，2021/01-2023/12，24万元，在研，主持。

2. 山西省应用基础研究项目，201901D211136，肺炎克雷伯菌噬菌体的特性、基因组学及抗多药耐药菌感染的潜力研究，2019/09-2022/09，3万元，在研，主持。

3. 山西省高等学校科技创新项目，2019L0040，IncHI5质粒介导临床拉乌尔菌耐药基因获得及进化的机制研究，2019/07-2021/07，2万元，在研，主持。

4. 国家自然科学基金面上项目，82070691，结节硬化症糖原储积异常分子细胞生物学病理机制研究，2021/01-2024/12，58万元，在研，参加。

5. 国家青年科学基金项目，31801662，IncA/C质粒介导食源性副溶血弧菌ESBLs基因获得及进化的分子机制研究，2019/01-2021/12，22万元，在研，参加。

6. 国家自然科学基金面上项目，31671290，副溶血弧菌毒力基因表达的密度感应调控机制，2017/01-2020/12，60万元，已结题，参加。

7. 国家重点研发专项，2016YFC1200100，重要新发突发病原体发生与传播机制研究，2016/07-2018/12，58.5万元，已结题，参加。

招生专业：

学术型硕士：遗传学、微生物学

专业型硕士：生物与医药（生物工程、食品工程）

发表文章：

1. Jiao Feng^{#, *}, Liting Gao^#, Lu Li^#; Zhijun Zhang, Changxin Wu, Fei Li^*, Yigang Tong^*, Characterization and genome analysis of novel Klebsiella phage BUCT556A with lytic activity againstcarbapenemase-producing Klebsiella pneumoniae, Virus Research, 2021, 303: 0-198506.

2. Jiao Feng^#, Zhe Yin^#, Qiangyuan Zhao, Yachao Zhao, Defu Zhang, Xiaoyuan Jiang, Weili Wu, Weijun Chen, Hui Wang, Yajun Song, Yigang Tong, Jinglin Wang^*, Yanjun Li^*, and Dongsheng Zhou^*, Genomic Characterization of Novel IncFII-Type Multidrug Resistant Plasmids p0716-KPC and p12181-KPC from Klebsiella Pneumoniae, Scientific Reports, 2017, 7.

3. Jiao Feng^#, Yefeng Qiu^#, Zhe Yin^#, Weijun Chen, Huiying Yang, Wenhui Yang, Jie Wang, Yingjie Gao, Dongsheng Zhou^*, Coexistence of a novel KPC-2-encoding MDR plasmid and an NDM-1-encoding pNDM-HN380-like plasmid in a clinical isolate of Citrobacter freundii. Journal of Antimicrobial Chemotherapy, 2015, 70(11):2987.

4. Qifeng Sun^#, Jiao Feng^#, Yigang Tong, Luhua Liang, Fei Zhai, Rongwu Xiang, Genomic characterization of IncpA1763-KPC: IncFIIK7 type plasmids p13294-KPC and pA1966-NR from Klebsiella pneumoniae. Future Microbiology, 2020, 15(9):713-721.

5. Bing Li^#, Jiao Feng^#, Zhe Zhan, Zhe Yin, Qiyu Jiang, Ping Wei, Xingming Chen, Bo Gao, Jun Hou, Panyong Mao, Weili Wu, Weijun Chen, Yigang Tong, Jinglin Wang, Boan Li^*, Dongsheng Zhou^*, Dissemination of KPC-2-Encoding IncX6 Plasmids among Multiple Enterobacteriaceae Species in a Single Chinese Hospital, Frontiers in Microbiology, 2018, 9.

6. Haihong Fang^#, Jiao Feng^#, Yuanhong Xu, Ying Zhang, Zhe Zhan, Zhe Yin, Xiongbo Duan, Bo Gao, Yigang Tong, Jinglin Wang, Yanping Luo^*, Erhei Dai^*, and Dongsheng Zhou^*, Sequencing of pT5282-CTXM, p13190-KPC and p30860-NR, and Comparative Genomics Analysis of IncX8 Plasmids, International Journal of Antimicrobial Agents, 2018, 52: 210-217.

7. Lining Shi#, Feng Jiao#, Zhe Zhan, Yuzong Zhao, Haijian Zhou, Haifeng Mao, Yingjie Gao, Ying Zhang, Zhe Yin, Bo Gao, Yigang Tong, Yanping Luo, Defu Zhang*, Dongsheng Zhou*. Comparative analysis of blaKPC-2- and rmtB-carrying IncFII-family pKPC-LK30/pHN7A8 hybrid plasmids from Klebsiella pneumoniae CG258 strains disseminated among multiple Chinese hospitals, Infection and Drug Resistance, 2018.10, Volume 11: 1783~1793.

8. Chen Z, Li H, Feng J, Li Y, Chen X, Guo X, Chen W, Wang L, Lin L, Yang H, Yang W, Wang J, Zhou D, et al. NDM-1 encoded by a pNDM-BJ01-like plasmid p3SP-NDM in clinical Enterobacter aerogenes. Frontiers in Microbiology. 2015; 6: 294.

9. Sun F, Yin Z, Feng J, Qiu Y, Zhang D, Luo W, Yang H, Yang W, Wang J, Chen W, Xia P, Zhou D. Production of plasmid-encoding NDM-1 in clinical Raoultella ornithinolytica and Leclercia adecarboxylata from China. Frontiers in Microbiology. 2015; 6: 458.

10. Wang L, Fang H, Feng J, Yin Z, Xie X, Zhu X, Wang J, Chen W, Yang R, Du H, Zhou D. Complete sequences of KPC-2-encoding plasmid p628-KPC and CTX-M-55-encoding p628-CTXM coexisted in Klebsiella pneumoniae. Frontiers in Microbiology. 2015; 6: 838.

11. Shi L, Liang Q, Feng J, Zhan Z, Zhao Y, Yang W, Yang H, Chen Y, Huang M, Tong Y, Li X, Yin Z, Wang J, et al. Coexistence of two novel resistance plasmids, blaKPC-2-carrying p14057A and tetA(A) -carrying p14057B, in Pseudomonas aeruginosa. Virulence. 2017; 11: 1-6.

12. Sun F, Zhou D, Wang Q, Feng J, Feng W, Luo W, Liu Y, Qiu X, Yin Z, Xia P. Genetic characterization of a novel blaDIM-2-carrying megaplasmid p12969-DIM from clinical Pseudomonas putida. Journal of Antimicrobial Chemotherapy. 2016; 71: 909-912.

13. Dai X, Zhou D, Xiong W, Feng J, Luo W, Luo G, Wang H, Sun F, Zhou X. The IncP-6 Plasmid p10265-KPC from Pseudomonas aeruginosa Carries a Novel ΔISEc33-Associated blaKPC-2 Gene Cluster. Frontiers in Microbiology. 2016; 7: 310.

14. Sun F, Zhou D, Wang Q, Feng J, Feng W, Luo W, Zhang D, Liu Y, Qiu X, Yin Z, Chen W, Xia P. The first report of detecting the blaSIM-2 gene and determining the complete sequence of the SIM-encoding plasmid. Clinical Microbiology and Infection. 2016; 22: 347-351.

15. Shi L, Liang Q, Zhan Z, Feng J, Zhao Y, Chen Y, Huang M, Tong Y, Wu W, Chen W, Li X, Yin Z, Wang J, et al. Co-occurrence of 3 different resistance plasmids in a multi-drug resistant Cronobacter sakazakii isolate causing neonatal infections. Virulence. 2017; 3: 1-11.

16. Zhang D, Yin Z, Zhao Y, Feng J, Jiang X, Zhan Z, Wu W, Chen W, Wang J, Li J, Zhou D. p1220-CTXM, a pKP048-related IncFIIK plasmid carrying blaCTX-M-14 and qnrB4. Future Microbiology. 2017; 12: 1035-1043.

17. Liang Q, Yin Z, Zhao Y, Liang L, Feng J, Zhan Z, Wang H, Song Y, Tong Y, Wu W, Chen W, Wang J, Jiang L, et al. Sequencing and comparative genomics analysis of the IncHI2 plasmids pT5282-mphA and p112298-catA and the IncHI5 plasmid pYNKP001-dfrA. International Journal of Antimicrobial Agents. 2017; 49: 709-718.